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Updated: Jun 2, 2026
12:23
Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Drug-induced skin reactions].
Kaija Lammintausta1, Kristiina Alanko
1TYKS:n iho- ja sukupuolitautien klinikka PL 52, 20521 Turku.
Duodecim; Laaketieteellinen Aikakauskirja
|April 16, 2011
Summary
Drug reactions, often skin reactions like exanthema and urticaria, can be triggered by common medications such as antimicrobials and anti-inflammatories. Diagnosis relies on clinical presentation and patient history.
Area of Science:
- Dermatology
- Pharmacology
- Allergology
Context:
- Drug-induced skin reactions are a significant clinical concern.
- Various drug classes, including antimicrobials, anti-inflammatories, ACE inhibitors, antiepileptics, and anticancer agents, can precipitate these reactions.
- Common manifestations include exanthema and urticaria, with potential for angioedema or anaphylaxis.
Purpose:
- To outline the spectrum of drugs causing skin reactions.
- To identify common and severe types of drug-induced cutaneous adverse events.
- To emphasize the diagnostic approach to drug reactions.
Summary:
- Antimicrobials and anti-inflammatories are frequent culprits of drug-induced skin reactions.
- Other implicated drugs include ACE inhibitors, antiepileptics, and anticancer agents.
- Severe reactions like toxic epidermal necrolysis and Stevens-Johnson syndrome necessitate prompt recognition.
Impact:
- Enhances understanding of drug hypersensitivity.
- Aids clinicians in diagnosing and managing cutaneous drug reactions.
- Highlights the importance of clinical assessment and patient history in identifying causative agents.
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