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Updated: Jun 2, 2026

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
Published on: July 7, 2016
Efficacy and feasibility of pericardial endoscopy by a subcutaneous approach
Koichi Nagashima1, Ichiro Watanabe, Yasuo Okumura
1Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.
Abstract:
We tested the efficacy and feasibility of percutaneous subxiphoid video pericardial endoscopy in five dogs. After percutaneous subxiphoid puncture, steerable 9F endoscope and 7F irrigated-tip catheters were advanced into the epicardial space. Epicardial vessels were visualized, and basal fat was distinguishable. Lesions created by the irrigated-tip catheter could be also appreciated on the epicardial surface. The endoscopic pericardial procedure was successful and may increase the efficacy and safety of epicardial irrigated radiofrequency catheter ablation.
