Related Experiment Video
Updated: Jun 2, 2026

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
Alexithymia in irritable bowel syndrome.
1M.D., Senior Lecturer, Department of Psychiatry, Govt. Medical College Hospital, Sector 32, Chandigarh.
Irritable bowel syndrome (IBS) patients exhibit higher levels of alexithymia, depression, and neuroticism compared to controls. Alexithymia scores positively correlated with depression and neuroticism in IBS subjects.
Area of Science:
- Psychiatry
- Gastroenterology
- Psychosomatic Medicine
Background:
- Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder.
- Psychological factors are increasingly recognized as significant contributors to IBS symptomology and patient experience.
Purpose of the Study:
- To investigate the relationship between alexithymia, depression, neuroticism, and stress in individuals with IBS.
- To compare psychological profiles of IBS patients with healthy controls.
Main Methods:
- A comparative study involving 30 IBS patients and 30 healthy controls.
- Assessment of alexithymia, depression, neuroticism, and stress levels using standardized psychometric instruments.
Main Results:
- IBS patients demonstrated significantly higher scores for alexithymia, depression, neuroticism, and stress compared to the control group.
- Alexithymia showed a significant positive correlation with depression and neuroticism among IBS subjects.
- No significant correlation was found between stress scores and alexithymia in the IBS cohort.
Conclusions:
- Alexithymia is a relevant psychological trait associated with increased depression and neuroticism in IBS.
- These findings highlight the importance of addressing psychological comorbidities in the management of IBS.
- Further research may explore the clinical implications of alexithymia in IBS pathophysiology and treatment.
Related Concept Videos
Irritable Bowel Syndrome
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Irritable Bowel Syndrome III: Medical and Nursing Management

