Related Experiment Video
Updated: Jun 2, 2026
A Murine Model of Carotid Aneurysm Formation
Published on: September 9, 2025
[Biomechanical modelling of cerebral aneurysm generation]
1Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Bioinginerie Medicală, Disciplina de Biomecanică.
Unlabelled:
The mechanisms of production for these aneurysms were not very well explained, therefore, the paper presents the conditions and steps in this vascular deficiency generation.
Material And Methods:
The physiological overpressures were evaluated and the role of the compliance and hydraulic strength was determined by using windkessel model.
Results:
The mathematical model was performed on the internal carotid artery and it reveals the role of blood vessel compliance and the increasing of hydraulic vascular-parietal resistance, caused by the contractile dysfunctions of pre-capillary sphincters during the appearance of sac-like and physiological forms of aneurisms.
