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Propranolol: useful therapeutic agent for the treatment of ulcerated infantile hemangiomas

Lawrence H C Kim1, Marcia Hogeling2, Orli Wargon2

  • 1Department of Pediatric Surgery, Sydney Children's Hospital, Randwick, New South Wales, Australia.

Journal of Pediatric Surgery
|April 19, 2011
PubMed

Insights

Oral propranolol effectively treats ulcerated infantile hemangiomas (IH), the most common childhood vascular tumor. This treatment offers a promising first-line approach for managing this frequent and challenging complication.

Area of Science:

  • Pediatric Oncology
  • Dermatology
  • Vascular Biology

Background:

  • Infantile hemangioma (IH) is the most common vascular tumor in infants.
  • Ulceration is a frequent and difficult-to-manage complication of IH.

Observation:

  • Six cases of ulcerated infantile hemangioma were treated at a pediatric center.
  • All cases demonstrated positive response to oral propranolol therapy.

Findings:

  • Oral propranolol treatment led to resolution of ulcerated IH within 2 to 6 weeks.
  • The medication was effective in managing this common complication.

Implications:

  • Oral propranolol should be considered as a first-line treatment for ulcerated infantile hemangioma.
  • This approach may improve patient outcomes and reduce treatment challenges.

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