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Early Enteral Nutrition After Paediatric Ostomy Closure (EPOC): A Protocol for a Multicentre, Prospective Randomised

Joyce Ly1, James Cope1, Nicholas Olsen2

  • 1Discipline of Paediatrics and Child Health, School of Clinical Medicine, The University of New South Wales, Kensington, New South Wales, Australia.

Journal of Paediatrics and Child Health
|April 22, 2026
PubMed

Insights

This study investigates early enteral nutrition in children after surgery. Early feeding may improve outcomes and reduce hospital stays for pediatric patients undergoing elective enterostomy closure.

Area of Science:

  • Pediatric Surgery
  • Clinical Nutrition
  • Gastroenterology

Background:

  • Enterostomy closure in children can lead to delayed feeding and prolonged hospital stays.
  • Optimizing post-operative nutrition is crucial for recovery in pediatric surgical patients.

Purpose of the Study:

  • To assess the safety and efficacy of early enteral nutrition following elective enterostomy closure in children.
  • To compare early feeding initiation (within 24 hours) versus standard care (on return of bowel function).

Main Methods:

  • Prospective, multicentre, randomized controlled trial (RCT) involving 68 children aged 3 months to 16 years.
  • Stratified randomization by age, stoma type, and hospital.
  • Primary outcome: length of stay (hours). Secondary outcomes: time to oral feeds, time to stool, pain, complications, analgesia, parent satisfaction.

Main Results:

  • This section is not applicable as the study is ongoing and results are not yet available.

Conclusions:

  • This ongoing RCT will provide critical data on the benefits of early enteral nutrition in pediatric surgical patients.
  • Findings are expected to inform clinical practice guidelines for post-enterostomy closure care in children.
Abstract

Keywords:
ERASearly enteral nutritionintestinal anastomosispaediatric surgerystoma closure

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