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Related Experiment Video

Updated: Jun 2, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

[Proxy lymphomatoid contact dermatitis].

V Hospital¹, S Amarger, F Franck

¹Service de dermatologie, CHU, université Clermont-Ferrand, France. vhospital@chu-clermontferrand.fr

Annales De Dermatologie Et De Venereologie

|April 19, 2011

Summary

This summary is machine-generated.

This case study shows a rare instance of B-cell infiltration in lymphomatoid contact dermatitis, triggered by indirect allergen exposure. It emphasizes the importance of thorough patient history in diagnosing allergic reactions.

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Area of Science:

Dermatology
Allergology
Immunology

Background:

Lymphomatoid contact dermatitis typically involves T-cell infiltration.
This case presents a variant with predominant B-cell infiltration.

Observation:

A 32-year-old man presented with persistent, steroid-resistant cutaneous lesions.
Lesions included an infiltrated patch and eczematous areas.
Biopsy revealed dense dermal infiltration primarily of B cells.

Findings:

Patch testing identified paraphenylenediamine (PPD) as the allergen.
The allergen was traced to the patient's spouse's hair dye.
Complete remission occurred after allergen withdrawal.

Implications:

A single allergen can induce diverse lymphoid phenotypes.
Detailed patient history is crucial in allergology diagnosis.
Highlights indirect allergen exposure as a cause of contact dermatitis.