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Updated: Jun 2, 2026

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules
Published on: October 17, 2014
Adhesion models: from single to multiple asperity contacts
Polina Prokopovich1, Victor Starov
1Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, United Kingdom. p.prokopovich@leeds.ac.uk
Abstract:
This review presents a summary of the current adhesion models available to date, between real rough surfaces, starting from single asperity models and expanding to multiple asperity contacts. The focus is made on multi-asperity contact interactions. Both van der Waals and contact mechanics approaches have been considered and relevant adhesion models are reviewed and discussed. The influence of the meniscus forces on adhesion has been considered, along with a summary of the various meniscus models. The effect of surface geometry, its topography and environmental conditions on meniscus action are also discussed along with its integration into multi-asperity adhesion models.
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