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Updated: Jun 25, 2026

Microfluidic Synthesis of Microgel Building Blocks for Microporous Annealed Particle Scaffold
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Published on: June 16, 2022

Microgels prepared by microfluidics from structural design to practical applications: Development and challenge.

Mengdi Liu1, Congyi Xu1, Haiqi Chen1

  • 1College of Biosystems Engineering and Food Science, National-Local Joint Engineering Research Center of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory of Agro-food Resources and High-value Utilization, Fuli Institute of Food Science, Zhejiang University, Hangzhou 310058, China; Future Food Laboratory, Innovation Center of Yangtze River Delta at Zhejiang University, Zhejiang Engineering Research Center of Flexible Intelligent Manufacturing for Food, Key Laboratory of Synthesis and Application of Functional Structured Lipids of Zhejiang Province, Jiashan 314100, China.

Advances in Colloid and Interface Science
|June 23, 2026
PubMed
Summary
This summary is machine-generated.

Microfluidics enables precise fabrication of smart microgels for advanced applications. These responsive materials offer enhanced drug delivery, tissue engineering, and environmental solutions.

Keywords:
MicrofluidicsMicrogelsPractical applicationsSmart responsive behaviorsStructural construction

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Published on: July 18, 2018

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Last Updated: Jun 25, 2026

Microfluidic Synthesis of Microgel Building Blocks for Microporous Annealed Particle Scaffold
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Published on: June 16, 2022

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An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

Area of Science:

  • Biomaterials Science
  • Chemical Engineering
  • Nanotechnology

Background:

  • Microgels are 3D crosslinked polymeric networks with microscale dimensions, high surface area, and injectability.
  • They are crucial in drug delivery and tissue engineering.
  • Microfluidic technology offers precise control for synthesizing monodisperse microgels and complex architectures (e.g., core-shell, Janus).

Purpose of the Study:

  • To review microgels prepared via microfluidics, focusing on material selection, structural design, and smart responsive capabilities.
  • To discuss the enhancement of stimuli-responsive behaviors through precise structural control.
  • To highlight emerging applications and future prospects.

Main Methods:

  • Microfluidic synthesis for controlled microgel fabrication.
  • Structural engineering for complex architectures.
  • Integration of stimuli-responsive materials.

Main Results:

  • Microfluidics enables efficient synthesis of monodisperse and structurally complex microgels.
  • Precise structural control enhances stimuli-responsive behaviors.
  • Smart responsive microgels show promise in on-demand delivery, tissue engineering, and repair.

Conclusions:

  • Microfluidics is a powerful tool for developing advanced smart microgels.
  • These materials have significant potential in biomedicine and environmental applications.
  • Further research is needed to translate these findings into practical applications.