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Pax6 regulates boundary-cell specification in the rat hindbrain

Masanori Takahashi1, Noriko Osumi

  • 1Division of Developmental Neuroscience, United Centers for Advanced Research and Translational Medicine (ART), Graduate School of Medicine, Tohoku University, Seiryo-Machi, Aoba-ku, Sendai, Miyagi, Japan. mtaka@med.tohoku.ac.jp

Mechanisms of Development
|April 20, 2011
PubMed
Summary

Pax6 is crucial for specifying boundary cells and preventing neuronal differentiation in the developing rat hindbrain. Loss of Pax6 disrupts boundary region formation and leads to ectopic neurogenesis.

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