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DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
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Chemically programmed polymers for targeted DNA and siRNA transfection.

Eveline Edith Salcher1, Ernst Wagner

  • 1Department of Pharmacy, Pharmaceutical Biotechnology, Center for System-Based Drug Research, Ludwig-Maximilians University, Butenandtstrate 5-13, 81377 Munich, Germany.

Topics in Current Chemistry
|April 20, 2011
PubMed
Summary

Bioresponsive polymers offer a promising solution for delivering therapeutic nucleic acids like plasmid DNA and siRNA. These advanced materials mimic viruses, enhancing gene delivery efficiency and biocompatibility by adapting to the delivery environment.

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