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Disseminated Burkholderia gladioli infection in a lung transplant recipient with underlying hypocomplementemic
G R Thompson1, B L Wickes, M L Herrera
1Department of Medical Microbiology and Immunology, Division of Infectious Diseases, University of California-Davis, Davis, California 95616, USA. george.thompson@ucdmc.ucdavis.edu
Abstract:
Burkholderia gladioli is difficult to definitively identify within the laboratory using phenotypic testing alone. We describe a case of recurrent B. gladioli infection in a lung transplant recipient with underlying hypocomplementemic urticarial vasculitis syndrome, discuss the difficulties encountered with laboratory identification, provide a review of the methodology required for definitive identification, and discuss potential pathophysiologic mechanisms in this patient responsible for the difficulty in treatment.
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