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Updated: Jun 2, 2026

Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
Published on: June 14, 2020
[The histoarchitectonics of the pharyngeal tonsil in age aspect: morphometric and immunohistochemical study]
Abstract:
To assess immune responsiveness in children requires basic knowledge of the morphofunctional organization of the immune system that involves lymphoepithelial organs of Waldeyer's ring. Among them, the pharyngeal tonsil is the first to respond to both respiratory tract infection and local vaccination, which determines the need for investigations of its immune responsiveness when a child's immune system is developed. The morphometry of the histological structures of the pharyngeal tonsil and the cell immunophenotyping of this organ in age aspect are used to solve this task. The basic findings are needed to assess and compare different therapeutic approaches (vaccination and immunotherapy).
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