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Published on: October 10, 2025
Maternal periodontal status and preterm delivery: a hospital based case-control study
J K Baskaradoss1, A Geevarghese, V R Kutty
1Achutha Menon Centre for Health Science Studies (AMCHSS), Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Thiruvananthapuram, Kerala, India. drjaganb@gmail.com
Maternal periodontal disease is linked to a nearly threefold increased risk of preterm delivery. This study in Kerala, India, highlights the importance of oral health during pregnancy for preventing premature birth.
Area of Science:
- Obstetrics and Gynecology
- Periodontology
- Public Health
Background:
- Emerging evidence suggests a link between maternal periodontal disease and preterm delivery.
- This association has not been consistently confirmed in all populations.
- Investigating this link in diverse geographical regions is crucial for public health.
Purpose of the Study:
- To explore the association between maternal periodontal disease and preterm delivery.
- To assess the role of periodontal health in pregnancy outcomes in Kerala, India.
Main Methods:
- A case-control study involving 300 postpartum women (100 cases of preterm delivery, 200 controls of term delivery).
- Clinical and periodontal examinations were conducted.
- Multivariate logistic regression analysis was used to evaluate the association, controlling for other risk factors.
Main Results:
- Periodontitis was diagnosed in 25% of mothers with preterm delivery versus 14.5% of mothers with term delivery.
- Mothers with periodontitis had a nearly threefold increased risk of preterm delivery (adjusted odds ratio = 2.72).
- Other significant risk factors included physical exertion, previous preterm birth, and previous abortion/infant death.
Conclusions:
- Periodontal disease is identified as a potential risk factor for preterm delivery in the population studied.
- This finding underscores the importance of addressing maternal oral health to improve pregnancy outcomes.
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