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Related Experiment Video

Updated: Jun 2, 2026

Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos
07:16

Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos

Published on: August 18, 2022

DNA methylation in zebrafish.

Mary G Goll1, Marnie E Halpern

  • 1Developmental Biology Program, Sloan-Kettering Institute, New York, USA.

Progress in Molecular Biology and Translational Science
|April 22, 2011
PubMed
Summary
This summary is machine-generated.

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DNA methylation is vital for development. Zebrafish (Danio rerio) offer a powerful model to study DNA methylation, showing conservation with mammals and new research strategies.

Area of Science:

  • Epigenetics and Developmental Biology
  • Comparative Genomics

Background:

  • DNA methylation is essential for eukaryotic development and cellular differentiation.
  • The zebrafish (Danio rerio) is an emerging model organism for studying epigenetic mechanisms.
  • Understanding DNA methylation in zebrafish provides insights into conserved biological processes.

Purpose of the Study:

  • To review current knowledge of DNA methylation in zebrafish.
  • To highlight the conservation of DNA methylation systems between zebrafish and mammals.
  • To present novel strategies using zebrafish for key DNA methylation research questions.

Main Methods:

  • Literature review and synthesis of existing research on DNA methylation in zebrafish.
  • Comparative analysis of DNA methylation pathways in zebrafish and mammalian systems.

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High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping
10:12

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping

Published on: June 29, 2018

Related Experiment Videos

Last Updated: Jun 2, 2026

Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos
07:16

Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos

Published on: August 18, 2022

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping
10:12

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping

Published on: June 29, 2018

  • Identification and discussion of emerging research approaches utilizing the zebrafish model.

    • Main Results:

    • DNA methylation plays a critical role in zebrafish development and differentiation.
    • The zebrafish DNA methylation system exhibits significant conservation with that of mammals.
    • The zebrafish model is suitable for investigating fundamental questions in epigenetics.

    Conclusions:

    • Zebrafish serve as a valuable model for understanding conserved epigenetic mechanisms, particularly DNA methylation.
    • Further research in zebrafish can elucidate key unanswered questions in DNA methylation.
    • The conservation of DNA methylation highlights the utility of zebrafish in broader biological studies.