Related Experiment Video
Updated: Jun 2, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
[Incidence of central line-associated bloodstream infection in an intensive care unit]
M Espiau1, M Pujol, M Campins-Martí
1Unitat de Patologia Infecciosa i Immunodeficiències de Pediatria, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, España. mespiau@vhebron.net
Insights
Central line-associated bloodstream infections (CLABSI) are a significant concern in pediatric intensive care units (PICUs). Implementing a "Bacteraemia zero" program effectively reduced CLABSI incidence in pediatric patients.
Area of Science:
- Infectious Diseases
- Pediatric Critical Care
- Hospital Epidemiology
Context:
- Central line-associated bloodstream infection (CLABSI) is a prevalent nosocomial infection, particularly in pediatric intensive care units (PICUs).
- CLABSI contributes significantly to patient morbidity, necessitating effective prevention strategies.
- The incidence of CLABSI is notably higher in pediatric patients compared to adults.
Purpose:
- To evaluate the impact of a
Summary:
- An intervention study in a pediatric ICU assessed the
Impact:
- The
Background:
Central line-associated bloodstream infection (CLABSI) is one of the most common nosocomial infections. The incidence is higher in paediatric patients than in adults, especially in those admitted to Intensive Care Units (ICU). CLABSI-related morbidity makes it a major health problem; therefore it is necessary to develop prevention strategies against it.
Patients And Methods:
An intervention study in a paediatric ICU (PICU) was performed, in order to assess the impact of the introduction of the program «Bacteraemia zero» in December 2007. This program aims to prevent CLABSI. Demographic data and variables related to hospitalisation and infection were collected from January to December 2007 (before the intervention) and from January to December 2008 (after the intervention), and were compared. In the first period, 497 patients were studied, and 495 in the second.
Results:
A reduction of 30.4% in the incidence of CLABSI (P=0.49) in the second year was observed (5.5 to 3.8 episodes per 1000 catheter-days). The CVC use ratio was 0.59 and 0.64, respectively. The most frequently isolated organism was coagulase-negative Staphylococcus spp.
Conclusions:
The implementation of a «no bacteraemia» program, involving all staff in the PICU as well as the professionals in infection control, reduces the incidence of CLABSI.
Related Concept Videos
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Endocarditis IV: Nursing Management
Endocarditis I: Introduction
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...

