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Updated: Aug 17, 2026

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
Rate of elution of leachable components from composite
1Oregon Health Sciences University, Portland.
Abstract:
The uptake of solvent and the elution of molecules from a dental composite and an unfilled resin were monitored with time during soaking in either water or an ethanol/water mixture. The results showed that approximately 50% of the leachable species were eluted from the composite within three hours of soaking in water, while 75% of the leachable molecules were eluted into the ethanol/water mixture. Elution of nearly all of the leachable components was complete within a 24-hour period in either solvent. The study lends support to the view that dental composites do not provide a chronic source of unreacted monomer to the pulp or other oral tissues, due to a rapid and complete elution of the molecules.
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