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Updated: Jun 2, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
Severe Hyperparathyroidism Versus Parathyroid Carcinoma: A clinical dilemma
Mariam Al-Fadhli1, Suhail A R Doi, Thomas Muttikkal
1Department of Medicine, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait.
Abstract:
No clinical or laboratory data allow a preoperative diagnosis of parathyroid carcinoma and only occasionally does a definitive finding differentiate an adenoma from a carcinoma. We present a case of primary hyperparathyroidism presenting with severe elevation of parathyroid hormone and serum calcium as well as complications. We go on to discuss the case in the light of a literature review. The severity of the elevation of the parathyroid hormone, other biochemical alterations, the presence of skeletal and renal complications and of a neck mass should alert the clinician to a possible parathyroid carcinoma. Radical surgery is the only effective therapy for parathyroid carcinoma, and should always be performed if a preoperative suspicion is entertained.
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