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Updated: Jun 2, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Adie's pupil during migraine attack: case report and review of literature
Abbas Tafakhori1, Vajiheh Aghamollaii, Amirhossein Modabbernia
1Iranian Center for Neurological Research, Department of Neurology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:
Association of migraine and tonic pupil has been reported very rarely. We reported a young female with symptoms of migraine who developed a mydriatic pupil in one of her attacks. The pupil was unresponsive to light with little response to near reflex. In 0.125% pilocarpine test affected pupil responded significantly and tonic pupil was diagnosed. The patient's problem became severe after a one-year follow up. We discussed possible mechanisms and reviewed previous cases with the same diagnosis. Evidences show that this association may be caused by infarction of parasympathetic fibers secondary to prolonged vasospasm which sometimes occurs in migraine.
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