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Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
Published on: January 27, 2019
Trypanosoma cruzi I diversity: towards the need of genetic subdivision?
Felipe Guhl1, Juan David Ramírez
1Centro de Investigaciones en Microbiología y Parasitología Tropical, CIMPAT, Universidad de los Andes, Cra 1 No. 18A-10, Bogotá, Colombia. fguhl@uniandes.edu.co
Abstract:
Trypanosoma cruzi the aethiological agent of Chagas disease, a complex zoonoses that affects the American continent is a genetically variable parasite subdivided into six Discrete Typing Units (DTUs). T. cruzi I is the most prevalent DTU affecting the northern countries of America with sporadical cases in the southern countries. T. cruzi I has shown great genetic diversity showing plausible subdivisions needed for this group. Recently, TcI has gained novel importance because of the lately discovered relation with cardiomyopathy manifestations that raises the importance of establishing subdivisions within this DTU.
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