Related Experiment Video
Updated: Jun 2, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
MDCT findings in Baastrup disease: disease or normal feature of the aging spine?
Yune Kwong1, Nitin Rao, Khalid Latief
1Department of Radiology, Nottingham University Hospitals, United Kingdom. dryune@hotmail.com
Objective:
Baastrup disease is characterized by the development of abnormal contact between adjacent spinous processes. The clinical significance remains unresolved, a few studies showing Baastrup disease as a cause of back pain. The aim of this study was to establish the frequency of Baastrup disease in a large unselected cohort to determine whether it is part of the expected spectrum of degenerative changes in the aging spine.
Materials And Methods:
The abdominopelvic CT scans of 1008 patients divided equally into seven age groups were retrospectively reviewed. Baastrup disease was judged present if there was close contact between adjacent spinous processes and if the apposing ends were sclerotic. The presence of other degenerative changes, such as disk degeneration, spondylolisthesis, and facet osteoarthritis, at affected levels also was noted.
Results:
Evidence of Baastrup disease was found in 413 patients (41.0%). A decade-on-decade increase in frequency was found with a peak of 81.3% among patients older than 80 years. As many as five levels were found to be affected in some patients (4.1% of 413), but in most patients (35.4%), one level was affected. Baastrup disease was most common at L4-L5. Associated degenerative changes were found at almost all affected levels (899/901).
Conclusion:
Baastrup disease occurs with high frequency among the elderly. Our data show that it develops with increasing age and is part of the expected degenerative changes in the aging spine. Because of the nearly universal association with other degenerative changes, we urge caution before diagnosing Baastrup disease as the cause of back pain.
Related Concept Videos
Degenerative Disc Disease I: Introduction
Degenerative Disc Disease ll: Pathophysiology
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
