Related Experiment Video
Updated: Jun 2, 2026
Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
Published on: February 13, 2016
pH- and Temperature-Responsive P(DMAEMA-GMA)-Alginate Semi-IPN Hydrogels Formed by Radical and Ring-Opening
Chunmei Gao1, Mingzhu Liu, Jun Chen
1a State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and Department of Chemistry, Lanzhou University, Lanzhou 730000, P. R. China.
Abstract:
A novel poly((2-dimethylamino) ethyl methacrylate-glycidyl methacrylate)-alginate (P(DMAEMA-GMA)alginate) semi-IPN hydrogel was synthesized via radical polymerization of the double bonds and ring-opening of the epoxy groups without using catalyst and cross-linker. (1)H-NMR, FT-IR and DSC data were consistent with the expected structures for the hydrogels. The interior morphology of the hydrogels was also investigated by SEM. The swelling ratio and compressive strength of the hydrogels were measured. The semi-IPN hydrogel had pH and temperature sensitivity, and pH-sensitive points of all hydrogels were found to be at pH 5.0. The release behavior of the model drug, aminophylline, was found to be dependent on the hydrogel composition and environment pH, which manifests that these materials have potential applications as intelligent drug carriers.
More Related Videos
08:39Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release
Published on: July 4, 2017
12:07Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
Published on: April 16, 2018
Related Concept Videos
01:19Modified-Release Drug Delivery Systems: Rate-Programmed II
01:30Modified-Release Drug Delivery Systems: Stimuli-Activated