Related Experiment Video
Updated: Jun 2, 2026

A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation
Published on: June 10, 2020
[Clinical features and therapeutic measures of diffuse brain swelling in severe craniocerebral trauma]
Lu-Cheng Wei1, Wei-Xian Li, Jin-Quan Jiang
1Department Of Neurosurgery, Fifth Affiliated Hospital of Zunyi Medical College, Zhuhai 519100, China.
Objective:
To investigate the clinical features of diffuse brain swelling following severe craniocerebral trauma and explore the optimized treatment protocols.
Methods:
A total of 134 cases of craniocerebral trauma with diffuse brain swelling receiving surgical treatment (n=76) and conservative therapy (n=580) were analyzed retrospectively for the clinical outcomes.
Results:
Of the 76 surgical patients, 55 survived with a survival rate of 72.4% as compared with the rate of (75.9%, 43/58) in the conservative therapy group.
Conclusion:
Early implementation of comprehensive measures is of critical importance in the management of severe craniocerebral trauma with diffuse brain swelling.
Related Concept Videos
Cerebral Edema ll: Pathophysiology
Cerebral Edema l: Introduction
Traumatic Brain Injury l: Introduction
Brain Abscess l: Introduction
Increased Intracranial Pressure ll: Pathophysiology
Increased Intracranial Pressure l: Introduction

