[Endodontic treatment in patients at risk]

Area of Science:

• Dentistry
• Nephrology
• Immunology

Background:

• Patients with renal engraftment (kidney transplants) often undergo cytostatic therapy, leading to a suppressed immune system.
• This immunosuppression increases the risk of complications and treatment failure in dental procedures, including endodontic therapy.
• Periapical processes in such patients pose a significant clinical challenge due to heightened health risks.

Observation:

• The case describes endodontic treatment for a periapical process in a kidney transplant recipient.
• The patient was on continuous cytostatic therapy, compromising immune function.
• Potential for endodontic treatment failure and adverse health outcomes was a primary concern.

Findings:

• Detailed preparation and specific premedication protocols are crucial for managing high-risk patients.
• The endodontic therapy was performed with meticulous attention to the patient's compromised health status.
• Successful treatment necessitates a carefully planned and executed interdisciplinary approach.

Implications:

• This case highlights the importance of specialized endodontic management for immunocompromised patients.
• Interdisciplinary collaboration between dental professionals and nephrologists/immunologists is essential for patient safety and treatment success.
• The described protocols can serve as a guideline for managing similar complex cases in clinical practice.