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Updated: Jun 2, 2026

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Published on: June 3, 2022
Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and
Yasutaka Anraku1, Akihiro Kishimura, Atsushi Kobayashi
1Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Abstract:
Selective disposition of nanocarriers into target tissue is an essential issue in drug delivery. Critical size of nanocarriers (∼150 nm) discriminating the permeability into normal and tumor tissues was determined by the use of size-tunable, polyion complex hollow vesicles (PICsome) as a ruler.
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