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Published on: August 18, 2023
Human rabies among the paediatric population in Bangladesh
A C Dey1, M Shahidullah, M A Hossain
1Department of Neonatology, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka, Bangladesh.
Insights
Children aged 5-10 years are most at risk for rabies, often from stray animal bites. Most unvaccinated children did not receive post-exposure prophylaxis, highlighting a critical gap in rabies prevention.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Rabies remains a significant public health concern, particularly in pediatric populations.
- Understanding the epidemiological patterns of rabies in children is crucial for effective prevention and control strategies.
Purpose of the Study:
- To investigate the clinical presentation, at-risk age groups, vaccination status, and incubation periods of rabies in children.
- To identify key risk factors and patterns associated with rabies infection in a pediatric cohort.
Main Methods:
- A cross-sectional study was conducted at the Infectious Disease Hospital (IDH), Dhaka, over one year (July 2008-June 2009).
- Data was collected from case sheets of 70 children under 15 years with clinically diagnosed rabies.
- Information included age, gender, geographical origin, bite details, vaccination status, animal type, and incubation period.
Main Results:
- The most affected age group was 5-10 years (44.3%), with a male predominance (3:1).
- Most cases (84.3%) were from rural areas, with bites predominantly on limbs (75.7%) and from stray dogs (97.1%).
- A significant majority (84.3%) were unvaccinated, and the mean incubation period was 45.38 days (range: 11-150 days).
Conclusions:
- Children aged 5-10 years are most vulnerable to rabies.
- Bites from stray animals, particularly dogs, are the primary transmission route.
- Inadequate post-exposure prophylaxis uptake is a major concern, necessitating improved public health interventions.
Abstract:
This cross sectional study in the Infectious Disease Hospital (IDH), Mohakhali, Dhaka on rabies affected paediatric population was carried out to see the patterns of presentation, age group at risk, state of vaccination following animal exposure and the interval between animal exposure and the development of the disease. This one year study included the patients aged less than 15 years with clinically diagnosed rabies referred to the IDH between July 2008 and June 2009. Data was collected from the case sheets of rabies patients given by the relatives and attendants of the victims. A total of 70 cases were included in the study. In the present study most common age group were 5 to 10 years of age with 31(44.3%) patients followed by less than 5 years 23(32.9%) and the rest 16(22.9%) were more than 10 years of age. The male female ratio was 3:1. Among the 70 patients 59(84.3%) were from rural areas and only 11(15.7%) were from urban areas. Sixty six (94.3%) patients presented with bleeding from the site of injury and 4(5.7%) were without bleeding. Among the patients 53(75.7%) presented with bite on the limbs followed by bite on the face 8(11.4%), body 5(7.1%) and head 4(5.7%) cases. Thirty nine of the cases (55.7%) presented with multiple bites and 31(44.3%) had single bite. More than half that is 37(52.9%) patients presented with severe bite, 31(44.3%) had moderate bite and only 2(2.9 %) patients presented with mild bite. Fifty nine (84.3%) patients were unvaccinated whereas 11(15.7%) had history of vaccination after bite. Fifty two (74.3%) gave the history of bite by stray animal, 10(14.3%) by known rabid animal whereas 8(11.4%) had the history of bite by pet animal. Sixty eight patients (97.1%) had the history of bite by dog whereas 2(2.9%) reported cat bite. The mean±SD incubation period 45.38±26.91 days and range was 11-150 days. In the present study it is concluded that the 5-10 years group children were affected most, bites were mostly by stray animal, most of the children did not get post exposure prophylaxis and incubation period was between 11 to 150 days.
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