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Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
5,5'-Bis[(1H-imidazol-1-yl)meth-yl]-2,2'-bipyridine methanol disolvate
Abstract:
The title compound, C(18)H(16)N(6)·2CH(3)OH, was prepared by the reaction of 5,5'-bis-(bromo-meth-yl)-2,2'-bipyridine with imidazole. The main mol-ecule lies on an inversion center located at the mid-point of the C-C bond joining the two pyridine rings. The asymmetric unit therefore contains one half-mol-ecule and one methanol solvent mol-ecule. The dihedral angle between the pyridine and imidazole rings is 72.32 (5)°. In the crystal, weak inter-molecular O-H⋯N, C-H⋯N and C-H⋯O hydrogen bonds contribute to the stabilization of the packing.
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