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[Barrett esophagus. Frequency, endoscopic, histologic, and clinical characteristics]
R Piñero1, A Salomón, R González
1Servicio de Gastroenterología, Hospital Vargas de Caracas.
G.E.N
|January 1, 1990
Summary
Barrett's Esophagus (BE) was diagnosed in 0.24% of 9210 upper gastrointestinal endoscopies. This study found no dysplasia, highlighting the need for prospective trials to confirm BE prevalence.
Area of Science:
- Gastroenterology
- Oncology
Context:
- Upper gastrointestinal endoscopy is a common diagnostic procedure.
- Barrett's Esophagus (BE) is a premalignant condition.
- Previous studies have established risk factors for BE and esophageal adenocarcinoma.
Purpose:
- To determine the prevalence of Barrett's Esophagus (BE) in a large cohort undergoing upper gastrointestinal endoscopy.
- To characterize the endoscopic and histological features of diagnosed BE cases.
- To assess the presence of dysplasia in BE patients.
Summary:
- A retrospective review of 9210 upper gastrointestinal endoscopic examinations identified 23 cases (0.24%) of Barrett's Esophagus (BE).
- The mean age of affected individuals was 50.60 years, with a male to female ratio of 1.3:1.
- Histological confirmation revealed cardiac type BE in 60.86% and intestinal type in 39.10%. No dysplasia was detected in any cases.
- Common endoscopic findings included finger-like projections (56.52%) and ulcers (21.73%).
- The low observed frequency may be due to the retrospective nature of the analysis.
Impact:
- The findings suggest a potentially low prevalence of BE in the studied population, warranting further investigation.
- The absence of dysplasia in this cohort requires careful consideration.
- The recognized risk of esophageal adenocarcinoma associated with BE underscores the importance of prospective studies to accurately determine prevalence and guide clinical management in the region.