Related Experiment Video
Updated: Jun 2, 2026

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
Published on: June 2, 2019
Coronary revascularization in diabetic patients: Current state of evidence
Mukesh Singh1, Rohit Arora, Vamsi Kodumuri
1Division of Cardiology, Department of Internal Medicine, Rosalind Franklin University of Medicine & Science/The Chicago Medical School, North Chicago, Illinois, USA.
Insights
Diabetic patients undergoing coronary revascularization have worse outcomes. Optimal strategies for percutaneous coronary intervention versus surgical revascularization in diabetics with multivessel disease require further evidence.
Area of Science:
- Cardiology
- Diabetology
- Interventional Cardiology
Background:
- Diabetic patients represent a growing population undergoing coronary revascularization.
- These patients exhibit poorer outcomes compared to non-diabetic individuals.
- Current evidence for optimal revascularization strategy in diabetics is limited.
Purpose of the Study:
- To summarize the current evidence on coronary revascularization strategies for diabetic patients.
- To address the uncertainty surrounding the optimal approach in the context of advancing treatments.
- To provide data to guide decision-making for diabetic patients with multivessel coronary artery disease.
Main Methods:
- Review of current evidence on percutaneous coronary intervention (PCI) and surgical revascularization.
- Analysis of data concerning drug-eluting stents and newer antiplatelet agents.
- Focus on diabetic patients with multivessel coronary artery disease.
Main Results:
- Diabetic patients undergoing PCI or surgical revascularization have worse outcomes.
- The optimal revascularization strategy remains unclear due to advancements in both PCI and surgical techniques.
- Limited data exists for current treatment choices in this specific population.
Conclusions:
- The optimal coronary revascularization strategy for diabetic patients with multivessel coronary artery disease is not definitively established.
- Further research is needed to guide the choice between PCI and surgical revascularization in this high-risk group.
- Advancements in pharmacotherapy and technology necessitate updated evidence for clinical decision-making.
Abstract:
Although diabetic patients constitute an increasing number of individuals undergoing percutaneous coronary intervention (PCI) and surgical revascularization, they experience worse outcomes than nondiabetic patients. The optimal coronary revascularization strategy in the diabetic population remains unclear in view of advancements in pharmacotherapy and technology of both PCI and surgical revascularization. Data to guide decision making are limited regarding the current choice between coronary artery bypass graft surgery and PCI using drug-eluting stents and newer antiplatelet agents in diabetic patients with multivessel coronary artery disease. The present article summarizes the current state of evidence for coronary revascularization in the diabetic population.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Diabetic Retinopathy
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
