Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

Cushing Syndrome II: Pathophysiology

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...

Increased Intracranial Pressure ll: Pathophysiology

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Case Report: Corneal Ulceration from Bilateral Ectropion Due to Congenital Ichthyosis.

Optometry and vision science : official publication of the American Academy of Optometry·2019

Same author

Painful ophthalmoplegia as an initial presentation of sarcoidosis.

Clinical & experimental optometry·2016

Same author

Staging glaucoma using Stratus OCT in a U.S. veteran population.

Optometry and vision science : official publication of the American Academy of Optometry·2014

Same author

Monitoring keratitis resolution with optical coherence tomography.

Optometry and vision science : official publication of the American Academy of Optometry·2014

Same authorSame journal

Central corneal thickness measurements obtained with anterior segment spectral domain optical coherence tomography compared to ultrasound pachymetry in healthy subjects.

Optometry (St. Louis, Mo.)·2012

Same author

Spectral domain optical coherence tomography of myopic traction maculopathy.

Optometry (St. Louis, Mo.)·2011

Search research articles

Related Experiment Video

Updated: Jun 2, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Sturge-Weber syndrome and glaucoma.

Lindsay Basler¹, Joseph Sowka

¹Nova Southeastern University, College of Optometry, Ft. Lauderdale, FL 33328, USA. Lindsay.basler@gmail.com

Optometry (St. Louis, Mo.)

|April 29, 2011

Summary

Sturge-Weber syndrome (SWS) is a rare disorder causing malformations. Glaucoma is the most frequent ocular complication associated with SWS, requiring clinical awareness.

Area of Science:

Ophthalmology
Neurology
Genetics

Background:

Sturge-Weber syndrome (SWS) is a congenital disorder within the phakomatoses group.
Characterized by hamartomatous malformations affecting the eyes, skin, and central nervous system.
Ocular complications, notably glaucoma, are frequently observed in SWS patients.

Observation:

A 66-year-old male patient with a known history of Sturge-Weber syndrome and pre-existing glaucoma was evaluated.
This case highlights the clinical presentation of SWS with associated ocular disease.

Findings:

Glaucoma represents the most common ocular complication in individuals with Sturge-Weber syndrome.
Awareness of potential cutaneous, neurological, and ocular manifestations is crucial for managing SWS.

More Related Videos

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

Related Experiment Videos

Last Updated: Jun 2, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

Implications:

Early detection and management of glaucoma in SWS patients are essential for preserving vision.
This underscores the importance of multidisciplinary care for individuals with Sturge-Weber syndrome.
Further research into the pathogenesis of SWS-associated glaucoma may improve treatment strategies.