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Related Experiment Video

Updated: May 2, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

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Monitoring keratitis resolution with optical coherence tomography.

Angeline Hixson¹, Smith Blanc, Joseph Sowka

¹*OD †OD, FAAO Nova Southeastern University, College of Optometry, Ft. Lauderdale, Florida (all authors).

Optometry and Vision Science : Official Publication of the American Academy of Optometry

|March 19, 2014

Summary

This summary is machine-generated.

Spectral-domain optical coherence tomography (SD-OCT) offers an objective method for monitoring corneal edema and stromal keratitis, improving upon traditional biomicroscopy. This technique precisely quantifies corneal thickness changes during treatment for conditions like disciform keratitis.

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Area of Science:

Ophthalmology
Medical Imaging

Background:

Biomicroscopy is the standard for monitoring stromal keratitis and edema, often supplemented by photography or ultrasound pachymetry.
Spectral-domain optical coherence tomography (SD-OCT) is typically used for posterior segment examination but shows potential for anterior segment conditions.

Observation:

Two cases of disciform keratitis were monitored using SD-OCT with anterior segment software.
SD-OCT precisely quantified decreasing corneal edema and thickness throughout treatment.
Microcystic edema and keratic precipitates were accurately localized.

Findings:

SD-OCT provided objective measurements of corneal thickness, enabling precise tracking of therapeutic interventions.
The study demonstrated SD-OCT's utility in assessing the resolution of corneal edema.

Implications:

SD-OCT offers a more accurate method than biomicroscopy alone for monitoring stromal keratitis and corneal edema.
This technology enhances the objective assessment of treatment efficacy for corneal conditions.