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Updated: Jun 2, 2026

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker
07:47

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker

Published on: September 15, 2023

Clinical significance of integrin alpha 6 mRNA expression in gastric carcinoma

K Mimori1, M Mori, N Begum

  • 1KYUSHU UNIV,MED INST BIOREGULAT,DEPT SURG,BEPPU,OITA 874,JAPAN. OITA PREFECTURAL HOSP,DEPT SURG,BUNYOU,OITA,JAPAN. UNIV MASSACHUSETTS,MED CTR,DEPT MED,DIV DIGEST DIS & NUTR,WORCESTER,MA.

International Journal of Oncology
|April 30, 2011
PubMed

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Activation of Integrins

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Intracellular Signaling Affects Focal Adhesions

Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
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