Metastatic melanoma: an unusual presentation
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Updated: Jun 2, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Ferdinando De Vita1, Guido Giordano, Alessio Fabozzi
1Division of Medical Oncology, F. Magrassi-A. Lanzara Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, II Policlinico, Naples.
Abstract:
In this report we describe a case of a malignant cutaneous melanoma metastasizing to the pleural surface and peritoneal cavity 5 years after surgical resection of the primary lesion. Malignant cutaneous melanoma is a very aggressive cancer able to metastasize anywhere in the body. Pleural secondary lesions represent a rare event described only in a small number of patients and the association with peritoneal localizations may suggest an uncommon pattern of spread that we discuss.
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