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Updated: Jun 2, 2026
06:18
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
Chikungunya virus, southeastern France
Marc Grandadam1, Valérie Caro, Sébastien Plumet
1Institut Pasteur, Paris, France. marc.grandadam@pasteur.fr
Emerging Infectious Diseases
|May 3, 2011
Summary
Chikungunya virus autochthonous transmission occurred in France in 2010, facilitated by the Aedes albopictus mosquito. Viral genome analysis revealed novel features suggesting potential European emergence and spread.
Area of Science:
- Virology
- Epidemiology
- Medical Entomology
Background:
- Chikungunya virus (CHIKV) is a mosquito-borne alphavirus causing febrile illness.
- Autochthonous transmission signifies local virus spread, not imported cases.
- The presence of Aedes albopictus mosquitoes in Europe poses a risk for CHIKV introduction and transmission.
Purpose of the Study:
- To report the first autochthonous transmission of chikungunya virus in southeastern France.
- To analyze the genetic characteristics of locally transmitted CHIKV strains.
- To assess the implications of these findings for CHIKV emergence in Europe.
Main Methods:
- Surveillance for CHIKV infections in southeastern France.
- Mosquito vector identification and distribution assessment.
- Viral genome sequencing and phylogenetic analysis of CHIKV isolates.
Main Results:
- Confirmed autochthonous CHIKV transmission in September 2010.
- Identified Aedes albopictus as the likely local vector.
- Sequence analysis revealed specific viral genome features in local isolates.
Conclusions:
- The 2010 CHIKV outbreak in France demonstrates local transmission potential.
- Genetic features of the virus may influence its adaptation and spread in European environments.
- Ongoing surveillance is crucial to monitor CHIKV emergence in non-endemic regions.
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