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The serum level of interleukin-6 in patients with intellectual disability and refractory epilepsy
Kai A Lehtimäki1, Suvi Liimatainen, Jukka Peltola
1Department of Neurosurgery, Tampere University Hospital, Teiskontie 35, Tampere, Finland. kai.lehtimaki@pshp.fi
Abstract:
We aimed to study the influences of active epilepsy and intellectual disability (ID) on the serum interleukin-6 (IL-6) by determining levels in 74 patients with developmental disorder with epilepsy and 63 healthy controls. The patients showed significantly higher IL-6 levels than the controls (4.1±4.5pg/ml vs. 2.1±1.0pg/ml; p<0.001). High seizure frequency and severe intellectual disability emerged as predictors for elevated serum levels of IL-6.
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