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Updated: Jun 2, 2026

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A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
Published on: August 4, 2021
Minimally invasive surgery in the neonate
Joachim F Kuebler1, Benno M Ure
1Department of Pediatric Surgery, Hannover Medical School, Hannover, Germany. kuebler.joachim@mh-hannover.de
Seminars in Fetal & Neonatal Medicine
|May 3, 2011
Summary
Minimally invasive surgery in neonates is now feasible due to new techniques, but more data is needed to confirm its benefits over traditional surgery.
Area of Science:
- Neonatal surgery
- Minimally invasive surgical techniques
- Pediatric surgery
Background:
- Minimally invasive surgery (MIS) in neonates faced challenges due to limited space and unique physiology.
- Recent advancements in instruments and techniques have overcome initial obstacles.
- MIS is increasingly feasible and favored in specialized neonatal care centers globally.
Purpose of the Study:
- To review recent developments in neonatal minimally invasive surgery.
- To evaluate the existing evidence supporting the benefits of MIS in neonates compared to conventional surgery.
Main Methods:
- Literature review of recent advancements in neonatal MIS.
- Analysis of published data on the feasibility and outcomes of neonatal MIS.
- Examination of comparative studies between MIS and conventional surgery in neonates.
Main Results:
- New instruments and techniques have made neonatal MIS feasible for various procedures.
- While feasibility is documented, robust data on the superiority of MIS over conventional surgery is limited.
- Evidence supporting the benefits of MIS in neonates is still emerging.
Conclusions:
- Minimally invasive surgery is a viable option for neonates, driven by technological progress.
- Further research is crucial to establish definitive benefits of neonatal MIS.
- Comparative studies are needed to guide the widespread adoption of MIS in neonatal surgical care.

