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Humanized Mediator Release Assay as a Read-Out for Allergen Potency
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Humanized Mediator Release Assay as a Read-Out for Allergen Potency

Published on: June 29, 2021

Potency variability in diagnostic allergen extracts: is there an optimal strength?

Richard W Weber

    Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
    |May 3, 2011
    PubMed
    Summary

    No abstract available in PubMed .

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    The potency of a drug is the measure of its ability to produce a biological response and can be compared by looking at the half-maximum effective concentration or EC50 values of different drugs. A lower EC50 value indicates higher potency of the drug. In the dose–response curve of two antihypertensive drugs, candesartan and irbesartan, a significant difference is observed in their EC50 values. A lower EC50 value for candesartan indicates that it is more potent than irbesartan, as it produces...
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