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Related Experiment Video

Updated: Jun 2, 2026

Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

Quantifying gait impairment in multiple sclerosis using GAITRite technology.

Jacob J Sosnoff1, Madeline Weikert, Deirdre Dlugonski

  • 1Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, United States. jsosnoff@illinois.edu

Gait & Posture
|May 3, 2011
PubMed
Summary
This summary is machine-generated.

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The functional ambulatory profile (FAP) score effectively measures gait impairment in multiple sclerosis patients with early walking difficulties. This validated tool correlates well with disability and walking performance metrics.

Area of Science:

  • Neurology
  • Rehabilitation Science
  • Biomedical Engineering

Background:

  • Multiple Sclerosis (MS) significantly impacts mobility and quality of life.
  • Accurate assessment of gait impairment is crucial for managing MS progression.
  • The Functional Ambulatory Profile (FAP) score offers a potential new metric for gait analysis.

Purpose of the Study:

  • To investigate the validity of the Functional Ambulatory Profile (FAP) score derived from the GAITRite electronic walkway.
  • To assess the FAP score's correlation with established measures of disability and walking function in persons with multiple sclerosis (PwMS).

Main Methods:

  • A pilot study involving thirteen PwMS with Expanded Disability Status Scale (EDSS) scores of 4.0-6.0.
  • Participants completed four trials on the GAITRite pathway.

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  • Multidimensional walking assessment included performance tests (T25FW, TUG), self-report questionnaires (MSWS-12, LL-FDI), and accelerometry for free-living behavior.

    • Main Results:

    • The FAP score demonstrated strong correlations with neurological disability (EDSS, ρ=-0.81).
    • Significant correlations were found between FAP and walking performance metrics (T25FW, ρ=-0.82; TUG, ρ=-0.88).
    • Moderate correlations were observed with self-reported walking function (LL-FDI, ρ=0.81), impairment (MSWS-12, ρ=0.49), and free-living gait (accelerometry, ρ=0.52).

    Conclusions:

    • The FAP score is a valid and reliable marker for assessing gait impairment in PwMS experiencing the onset of walking difficulties.
    • The GAITRite system provides a valuable tool for quantifying gait abnormalities in multiple sclerosis.
    • FAP score shows promise for clinical use in monitoring MS-related mobility changes.