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Perspectives on biological growth and remodeling.
D Ambrosi1, G A Ateshian, E M Arruda
1Politecnico di Milano, Italy.
Journal of the Mechanics and Physics of Solids
|May 3, 2011
Summary
Biological growth and remodeling are studied using continuum mechanics. This review highlights current understanding and future research directions in experiments, theory, and computation.
Area of Science:
- Continuum mechanics
- Biological sciences
Background:
- Biological growth and remodeling are complex processes.
- Continuum mechanical approaches have gained traction over 15 years.
Purpose of the Study:
- To review the current state of continuum mechanical treatment of biological growth and remodeling.
- To identify open questions, challenges, and future research avenues.
Main Methods:
- Literature review and synthesis of existing research.
- Perspective analysis of experimental, theoretical, and computational aspects.
Main Results:
- Significant progress has been made in understanding biological growth and remodeling.
- Key areas requiring further development in experiments, theory, and computation have been identified.
Conclusions:
- The field of continuum mechanical modeling of biological growth and remodeling is advancing.
- Further interdisciplinary development is needed to address remaining challenges and unlock new avenues for research.
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