Related Experiment Video
Updated: Jun 2, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
May ingestion of leachate from decomposed corpses cause appendicitis? A case report
Maurício Domingues-Ferreira1, Pedro Saddi-Rosa, André Luis Dos Santos
1Hospital da Policia Militar, 04021-001 São Paulo, SP, Brazil.
Abstract:
The general consensus is that appendicitis is basically provoked by fecaliths or lymphoid hyperplasic obstruction. Several studies based on histological diagnosis have not confirmed this hypothesis. On the contrary, obstruction has been proved in only a minority of cases. Diverse infections by parasites, bacteria, fungus, and noninfective agents have been associated with appendicitis in the medical literature. We describe a firefighter, who ingested a small quantity of leachate from decomposing corpses while working and developed enteritis a few hours later, which lasted several days and evolved to appendicitis. This case raises the possibility that the high quantity of bacteria concentration present in the leachate could have provoked enteritis and the subsequent appendicitis due to a direct effect of the bacteria on the appendix.
Insights
Appendicitis may be caused by bacterial infections, not just obstruction. A case study suggests leachate ingestion led to enteritis and subsequent appendicitis, highlighting a potential direct bacterial effect.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Pathology
Background:
- The prevailing theory attributes appendicitis to fecaliths or lymphoid hyperplasia causing obstruction.
- However, histological studies have largely failed to confirm obstruction as a primary cause in most cases.
- Diverse infectious and noninfective agents have been anecdotally linked to appendicitis.
Observation:
- A firefighter developed enteritis after ingesting leachate from decomposing corpses.
- The enteritis persisted for several days before progressing to appendicitis.
- The leachate contained a high concentration of bacteria.
Findings:
- This case suggests a potential link between high bacterial load exposure and the development of appendicitis.
- The findings challenge the traditional obstruction-based hypothesis.
- Direct bacterial action on the appendix is proposed as a mechanism.
Implications:
- This case broadens the understanding of appendicitis etiology.
- It suggests infectious agents, particularly bacteria, may play a more direct role than previously thought.
- Further research into bacterial pathogenesis of appendicitis is warranted.
Related Concept Videos
Appendicitis
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Amebiasis
Cholecystitis
Intestinal Obstruction II: Pathophysiology
