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Updated: Jun 2, 2026
08:28
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
Published on: September 19, 2017
Analysis of the unbinding force between telomestatin derivatives and human telomeric G-quadruplex by atomic force
Yosuke Amemiya1, Yui Furunaga, Keisuke Iida
1Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan.
Chemical Communications (Cambridge, England)
|May 7, 2011
Abstract:
The force analysis between a macrocyclic hexazole (6OTD) monomer/dimer and telomeric DNA using atomic force microscopy revealed the difference in their binding modes. The 6OTD dimer bound to the G-quadruplex more strongly than the monomer by sandwiching the G-quadruplex.
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