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Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Delayed cilioretinal artery occlusion after a hemiretinal vein occlusion
Malavika Subash1, Kamaljit S Balaggan, Hadi J Zambarakji
1Moorfields Eye Hospital, London, UK. Malavika_subash@hotmail.com
Insights
This case report details a delayed cilioretinal artery occlusion (CLRAO) following hemiretinal vein occlusion. The patient recovered vision despite initial visual field defects, highlighting potential risk factors.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
- Clinical Case Reports
Background:
- Retinal vascular occlusive events, including hemiretinal vein occlusion and cilioretinal artery occlusion (CLRAO), can lead to significant vision loss.
- Combined occlusions are rare, and the sequential development with a significant delay is not well-documented.
Observation:
- A case of sequential hemiretinal vein occlusion followed by a substantially delayed cilioretinal artery occlusion (CLRAO) is presented.
- Clinical findings were documented with color fundus and fluorescein angiography.
- Undiagnosed hypertension was identified as a systemic factor during the patient's examination.
Findings:
- The patient experienced an inferior visual field defect secondary to the CLRAO.
- Despite the occlusion, visual acuity recovered to 20/40 at the 6-month follow-up.
- Hypertension was initiated on treatment.
Implications:
- This case highlights the importance of thorough systemic evaluation in patients with retinal vascular occlusions.
- Understanding the sequential development and risk factors for combined occlusions can improve patient management.
- Delayed CLRAO following retinal vein occlusion warrants further investigation into underlying pathogenetic mechanisms.
Abstract:
The purpose of this study is to report a case of combined hemiretinal vein occlusion and cilioretinal artery occlusion (CLRAO), in which the development of the CLRAO was substantially delayed. This interventional case report illustrates the sequential development of a cilioretinal artery occlusion following a hemiretinal vein occlusion with colour fundus and fluorescein angiogram photographs. Systemic examination revealed previously unrecorded hypertension for which her general practitioner commenced treatment. The patient developed an inferior visual field defect however made a visual recovery to 20/40 at 6-month follow-up. In this report, the risk factors and the likely pathogenesis for such an event are studied.
