Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Adherens Junctions01:24

Adherens Junctions

Strong contact points between adjacent cells anchor them to each other, forming tissues. Such anchoring junctions are of two types –  adherens junctions and desmosomes. Adherens junctions are abundant in tissues such as  epithelium and endothelium, forming a continuous zone of adhesion called the adhesion belt. In other tissues, such as  heart muscle, they appear as clusters, linking the cells to produce coordinated heart muscle contraction.
Adherens Junctions are Dynamic
The endothelial cells...
Adhesion01:14

Adhesion

Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow glass...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precision oncology without borders: the role of biobanking in integrating Africa's genetic diversity into global genomic research.

NPJ precision oncology·2026
Same author

Engineering human peritoneum in vitro: A novel microfluidic platform for modeling peritoneal physiology and pathophysiology.

Bioengineering & translational medicine·2026
Same author

Immunohistochemical Analysis of pH-Sensitive TRPV5 in Common Skin Tumors.

International journal of molecular sciences·2026
Same author

Structured micro-ultrasonography training improves prostate cancer detection and management decisions.

BJU international·2026
Same author

NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals.

BMC medicine·2026
Same author

Intraperitoneal G-CSF Stimulation Achieves Human-like Neutrophil Levels in NSG Mice Without Inducing Systemic Inflammation.

International journal of molecular sciences·2026

Related Experiment Video

Updated: Jun 2, 2026

Creation of Abdominal Adhesions in Mice
06:44

Creation of Abdominal Adhesions in Mice

Published on: August 27, 2016

Intraperitoneal adhesions--an ongoing challenge between biomedical engineering and the life sciences.

Christoph Brochhausen1, Volker H Schmitt, Taufiek K Rajab

  • 1REPAIR-Lab, Institute of Pathology, University Medical Centre of the Johannes Gutenberg-University, Mainz, Germany. brochhausen@pathologie.klinik.uni-mainz.de.

Journal of Biomedical Materials Research. Part A
|May 7, 2011
PubMed
Summary

Peritoneal adhesions are a clinical issue. Current barriers offer physical separation but aren't optimal, necessitating further research into material science and pharmacology for better prevention.

More Related Videos

BioMEMS: Forging New Collaborations Between Biologists and Engineers
07:26

BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007

Related Experiment Videos

Last Updated: Jun 2, 2026

Creation of Abdominal Adhesions in Mice
06:44

Creation of Abdominal Adhesions in Mice

Published on: August 27, 2016

BioMEMS: Forging New Collaborations Between Biologists and Engineers
07:26

BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007

Area of Science:

  • Surgical innovation
  • Biomaterials science
  • Gastroenterology

Background:

  • Peritoneal adhesions are a significant clinical challenge.
  • Current prophylactic barrier materials are insufficient for optimal adhesion prevention.
  • Understanding adhesion pathophysiology is crucial for developing new strategies.

Purpose of the Study:

  • To review current clinical strategies and innovations in peritoneal adhesion prevention.
  • To highlight the need for improved barrier materials.
  • To emphasize the role of mesothelial cells in adhesion formation.

Main Methods:

  • Review of existing literature on peritoneal adhesion formation.
  • Discussion of current barrier materials (liquid and solid).
  • Exploration of potential innovations, including material modification and pharmacological functionalization.

Main Results:

  • Physical separation using barriers is the primary strategy, but no optimal material exists.
  • Adhesion formation involves a complex cascade regulated by cellular and humoral factors.
  • Animal and human trials have not identified a universally effective barrier.

Conclusions:

  • Further development of barrier materials is essential for effective postoperative adhesion prevention.
  • Combining structural modification with pharmacological functionalization of barriers is a promising approach.
  • Collaboration between basic research, materials science, and clinical expertise is required.