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Nail biology, morphologic changes, and clinical ramifications: part II
Virendra N Sehgal1, Ashok K Aggarwal, Govind Srivastava
1Dermato-Venereology (Skin/VD) Center, Sehgal Nursing Home, Panchwati, Delhi. drsehgal@ndf.vsnl.net.in
This review covers pediatric nail changes, examining how cosmetics and ingested drugs affect nails. Nail biopsy is highlighted as a crucial diagnostic tool for identifying these changes.
Area of Science:
- Pediatric dermatology
- Nail biology and pathology
Background:
- Nail changes in children can stem from various external and internal factors.
- Understanding normal nail biology is essential for recognizing abnormalities.
Purpose of the Study:
- To review common nail changes observed in pediatric populations.
- To discuss the impact of cosmetic products and systemic drug ingestion on nail health.
- To emphasize the diagnostic value of nail biopsy.
Main Methods:
- Literature review of pediatric nail disorders.
- Analysis of case studies and clinical observations related to nail abnormalities.
- Discussion of histopathological findings from nail biopsies.
Main Results:
- Identified various nail alterations associated with cosmetic use.
- Documented nail manifestations resulting from oral or systemic drug administration.
- Highlighted the effectiveness of nail biopsy in diagnosing specific pediatric nail conditions.
Conclusions:
- Nail changes in children are diverse and can be linked to environmental exposures and medications.
- Nail biopsy provides critical diagnostic information for pediatric nail disorders.
- Awareness of these factors aids in the accurate diagnosis and management of pediatric nail conditions.
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