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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

Nevoid melanoma.

A Hafeez Diwan1, Alexander J Lazar

  • 1Department of Pathology, Baylor College of Medicine, Houston, TX, USA. ahdiwan@bmc.edu

Clinics in Laboratory Medicine
|May 10, 2011
PubMed
Summary
This summary is machine-generated.

This article details nevoid melanoma, covering its gross and microscopic characteristics, diagnostic methods, and treatment strategies for better understanding and management.

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Area of Science:

  • Dermatology
  • Pathology
  • Oncology

Background:

  • Nevoid melanoma is a rare melanocytic neoplasm.
  • Accurate diagnosis is crucial for appropriate management.

Purpose of the Study:

  • To comprehensively review the key features of nevoid melanoma.
  • To provide guidance on diagnosis and treatment.

Main Methods:

  • Review of existing literature on nevoid melanoma.
  • Discussion of diagnostic criteria including gross, microscopic, and immunohistochemical findings.

Main Results:

  • Detailed description of the characteristic gross and microscopic features.
  • Explanation of immunohistochemical markers aiding in diagnosis.
  • Outline of differential diagnoses to distinguish from similar lesions.

Conclusions:

  • Nevoid melanoma diagnosis relies on integrated assessment of morphological and immunohistochemical data.
  • Understanding its features aids in differentiating it from other melanocytic tumors.
  • Appropriate management strategies are essential for patient outcomes.