Related Experiment Video

Updated: Jun 2, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

[Specific features of tuberculosis in childhood]

C Delacourt1

  • 1Service de pneumologie pédiatrique, hôpital Necker-Enfants-Malades, 161, rue de Sèvres, 75015 Paris, France. christophe.delacourt@nck.aphp.fr

Revue Des Maladies Respiratoires
|May 10, 2011
PubMed

Insights

Primary childhood tuberculosis (TB) infection often comes from adults. This review details diagnosing and treating latent TB infection and active TB disease in children.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Context:

  • Primary Mycobacterium tuberculosis infection typically occurs in childhood, often from adult sources.
  • Childhood TB risk is influenced by the infectiousness of the primary case, exposure circumstances, and individual child factors.

Purpose:

  • To review the diagnostic challenges and therapeutic strategies for latent tuberculosis infection (LTBI) in children.
  • To outline the clinical features, diagnosis, and treatment of active tuberculosis disease in pediatric populations.

Summary:

  • This review synthesizes current knowledge on pediatric tuberculosis, focusing on primary infection dynamics.
  • It addresses the specific considerations for diagnosing and managing both latent TB infection and active TB disease in children.

Impact:

  • Provides essential information for clinicians managing pediatric TB cases.
  • Highlights the importance of understanding risk factors and tailored approaches for childhood tuberculosis.

More Related Videos

Growth of Mycobacterium tuberculosis Biofilms09:03

Growth of Mycobacterium tuberculosis Biofilms

Published on: February 15, 2012

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...