Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...
Multiple Comparison Tests01:13

Multiple Comparison Tests

Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved DNA...
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Speeding Up the Discovery of Optimal Feature Combinations for Omics Data Based on Pseudo-Kernel Function.

Research square·2026
Same author

Adaptation Outcomes of a CAPABLE-Family Open-Label Pilot Study for Community-Dwelling Older Adults With Mild Cognitive Impairment/Early Dementia and Disability.

Journal of applied gerontology : the official journal of the Southern Gerontological Society·2026
Same author

Anti-Tumor Activity of Cdk2/9 Inhibitor Fadraciclib in an In Vivo Model of Temozolomide Refractory Neuroblastoma.

Molecular cancer therapeutics·2026
Same author

Preparation and Characterization of Icariin-Loaded Bioactive Glass/Sodium Alginate Thermosensitive Composite Gel.

ACS applied bio materials·2026
Same author

Metabolic Syndrome and Gastric Cancer: A Concise Narrative Review of Recent Clinical Insights.

Current medicinal chemistry·2026
Same author

800 million years of co-evolution in the green plant lineage - the case of LEUNIG and SEUSS transcriptional co-regulators.

Molecular biology and evolution·2026
Same journal

3DICE: Interpretable 3D Cross-Modal Learning for Drug-Target Interaction Prediction and Large-Scale Drug Discovery.

Bioinformatics (Oxford, England)·2026
Same journal

KASSPer: Kinase Active Site Structure Prediction using Protein and Ligand Language Models and Its Application to Virtual Screening.

Bioinformatics (Oxford, England)·2026
Same journal

IDR searcher: a search engine solution for public image resources.

Bioinformatics (Oxford, England)·2026
Same journal

KCFtools: Rapid alignment-free method for introgression screening and GWAS using k-mer profiles.

Bioinformatics (Oxford, England)·2026
Same journal

Meta2DB: Curated shotgun metagenomic feature sets and metadata for health state prediction.

Bioinformatics (Oxford, England)·2026
Same journal

conMItion: an R package adjusting confounding factors for associations in multi-omics.

Bioinformatics (Oxford, England)·2026
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

Single Cell Multiplex Reverse Transcription Polymerase Chain Reaction After Patch-clamp
10:44

Single Cell Multiplex Reverse Transcription Polymerase Chain Reaction After Patch-clamp

Published on: June 20, 2018

An MCMC algorithm for detecting short adjacent repeats shared by multiple sequences.

Qiwei Li1, Xiaodan Fan, Tong Liang

  • 1Department of Statistics, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong.

Bioinformatics (Oxford, England)
|May 10, 2011
PubMed
Summary
This summary is machine-generated.

This study introduces a novel statistical method for detecting short adjacent repeats with insertions in biological sequences. The approach offers a competitive edge over existing methods for analyzing repeat-containing genes.

More Related Videos

Detection of Copy Number Alterations Using Single Cell Sequencing
09:45

Detection of Copy Number Alterations Using Single Cell Sequencing

Published on: February 17, 2017

Related Experiment Videos

Last Updated: Jun 2, 2026

Single Cell Multiplex Reverse Transcription Polymerase Chain Reaction After Patch-clamp
10:44

Single Cell Multiplex Reverse Transcription Polymerase Chain Reaction After Patch-clamp

Published on: June 20, 2018

Detection of Copy Number Alterations Using Single Cell Sequencing
09:45

Detection of Copy Number Alterations Using Single Cell Sequencing

Published on: February 17, 2017

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Traditional repeat detection methods struggle with gaps and multi-sequence patterns.
  • Existing techniques are insufficient for identifying short adjacent repeats with interunit insertions across multiple sequences.

Purpose of the Study:

  • To develop a novel method for detecting short adjacent repeats with interunit insertions from multiple biological sequences.
  • To enhance the understanding of molecular structure, function, and evolution through repeat analysis.

Main Methods:

  • Formulates repeat detection as a statistical inference problem using a probabilistic generative model.
  • Employs a Markov chain Monte Carlo algorithm for de novo parameter inference.

Main Results:

  • The proposed method demonstrates a competitive advantage over existing approaches.
  • Successfully applied to both synthetic and real biological data.
  • Provides insights into the structure and evolution of repeat-containing genes.

Conclusions:

  • The new statistical inference approach effectively detects short adjacent repeats with interunit insertions.
  • Offers a valuable tool for studying the evolutionary dynamics of repetitive elements in biological sequences.