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Updated: Jun 2, 2026

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Regulating Schwann Cell Growth by Nanosecond Pulsed Electric Field for Peripheral Nerve Regeneration In Vitro
Published on: May 3, 2024
Effects of human growth hormone on peripheral nerve regeneration
A Skottner1, M Kanje, V Arrhenius-Nyberg
1Kabi Peptide Hormones, Stockholm (Sweden).
Restorative Neurology and Neuroscience
|May 10, 2011
Abstract:
Systemic administration of human growth hormone (hGH) to intact or hypophysectomized rats was found to stimulate regeneration of the crush-lesioned sciatic nerve. The IGF-I levels of serum of the treated rats did not correlate with regeneration of the nerve but hGH treatment increased the IGF-I content of the nerve. The results suggest that a GH-mediated increase of IGF-I in the sciatic nerve could be involved in the stimulatory effect of GH on neurite outgrowth.

