Related Experiment Video
Updated: Jun 2, 2026

10:38
Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
Published on: September 9, 2015
Elephantine but not elephantiasis: Subcutaneous zygomycosis
Meenakshi Girish1, Amit Arora, Lucky Bhalla
1Departments of Pediatrics, NKP Salve Institute of Medical Science and Research Center, Nagpur, Maharashtra, India.
Indian Journal of Pediatrics
|May 10, 2011
Summary
Subcutaneous zygomycosis, a rare fungal infection, was diagnosed in a young boy. Treatment with saturated solution of potassium iodide led to rapid improvement, highlighting an effective therapeutic option.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Subcutaneous zygomycosis is an uncommon fungal infection.
- It is typically caused by the rare fungus Basidiobolus ranarum.
Observation:
- A case of subcutaneous zygomycosis in a 4-year-old boy is presented.
- Clinical presentation and diagnostic findings are detailed.
Findings:
- Biopsy revealed the characteristic Splendore Hoeppli phenomenon.
- Fungal culture confirmed the presence of Basidiobolus ranarum.
- The patient demonstrated a positive response to saturated solution of potassium iodide.
Implications:
- This case highlights the importance of recognizing subcutaneous zygomycosis.
- Saturated solution of potassium iodide is an effective treatment modality.
- Early diagnosis and treatment are crucial for favorable outcomes in pediatric fungal infections.
Related Concept Videos
Fungal Group Zygomycota
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Cryptococcal Meningitis
Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Fungal Phylum Microsporidia
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.