Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Methods of Documentation II: POMR01:26

Methods of Documentation II: POMR

The Problem-Oriented Medical Record (POMR) revolutionized medical record-keeping by introducing a systematic approach focusing on the patient's problems rather than merely listing symptoms. Dr. Lawrence Weed's introduction of this method in the 1960s marked a significant advancement in medical documentation. The POMR framework consists of four key components: the database, problem list, plan of care, and progress notes.
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biopsy with same-session MRI-guided laser interstitial thermal therapy versus biopsy alone in patients with primary unresectable glioblastoma: a multicentre randomised controlled trial.

The Lancet regional health. Europe·2026
Same author

Enhanced Recovery After Lumbar Fusion Surgery: An International Survey on Current Practice.

Global spine journal·2026
Same author

Evaluating dementia risk prediction in mild cognitive impairment: an early health technology assessment of the AI-Mind tool.

GeroScience·2026
Same author

Impact of multiparametric MRI and prostate biopsies on anxiety and quality of life in men with suspected prostate cancer.

BJUI compass·2025
Same author

Imaging-based techniques for ablation zone definition and volumetry after laser interstitial thermal therapy (LITT) for intracranial lesions: a systematic review.

Acta neurochirurgica·2025
Same author

Innovative Approaches to Improve the Success of Pituitary Surgery in Cushing's Disease: A Cost-Effectiveness Perspective.

Clinical endocrinology·2025
Same journal

Rheumatoid arthritis: previously untreated early disease.

BMJ clinical evidence·2016
Same journal

Diabetic retinopathy: intravitreal vascular endothelial growth factor inhibitors for diabetic macular oedema.

BMJ clinical evidence·2016
Same journal

Subarachnoid haemorrhage (spontaneous aneurysmal).

BMJ clinical evidence·2016
Same journal

Malaria: fluid therapy in severe disease.

BMJ clinical evidence·2016
Same journal

Age-related macular degeneration: anti-vascular endothelial growth factor treatment.

BMJ clinical evidence·2016
Same journal

MRSA: treating people with infection.

BMJ clinical evidence·2016
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy
07:20

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy

Published on: August 9, 2024

AOM in children.

Roger A J M Damoiseaux1, Maroeska M Rovers

  • 1General Practice de Hof van Blom, Hattem, The Netherlands.

BMJ Clinical Evidence
|May 11, 2011
PubMed
Summary
This summary is machine-generated.

Acute otitis media (AOM) in children often resolves without antibiotics. This review examines treatments and preventive strategies for AOM, evaluating effectiveness and safety to guide clinical decisions.

More Related Videos

Modeling Colitis-Associated Cancer with Azoxymethane (AOM) and Dextran Sulfate Sodium (DSS)
12:37

Modeling Colitis-Associated Cancer with Azoxymethane (AOM) and Dextran Sulfate Sodium (DSS)

Published on: September 11, 2012

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children
09:45

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children

Published on: April 29, 2013

Related Experiment Videos

Last Updated: Jun 2, 2026

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy
07:20

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy

Published on: August 9, 2024

Modeling Colitis-Associated Cancer with Azoxymethane (AOM) and Dextran Sulfate Sodium (DSS)
12:37

Modeling Colitis-Associated Cancer with Azoxymethane (AOM) and Dextran Sulfate Sodium (DSS)

Published on: September 11, 2012

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children
09:45

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children

Published on: April 29, 2013

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Evidence-Based Medicine

Background:

  • Acute otitis media (AOM) is a common childhood illness, frequently treated with antibiotics.
  • High antibiotic prescription rates for AOM exist despite spontaneous resolution in many cases.
  • AOM is a leading cause for antibiotic use in outpatient pediatric care.

Purpose of the Study:

  • To systematically review the effects of various treatments for AOM in children.
  • To evaluate interventions aimed at preventing recurrent AOM.
  • To synthesize evidence on the effectiveness and safety of AOM management strategies.

Main Methods:

  • Conducted a systematic review of medical literature up to September 2010.
  • Searched major databases including Medline, Embase, and The Cochrane Library.
  • Included data from systematic reviews, RCTs, observational studies, and harms alerts.

Main Results:

  • Included 29 systematic reviews, RCTs, or observational studies.
  • Performed GRADE evaluation to assess the quality of evidence for interventions.
  • Synthesized findings on a range of AOM interventions.

Conclusions:

  • The review presents information on the effectiveness and safety of multiple AOM interventions.
  • Interventions evaluated include analgesics, antibiotics (immediate, delayed, prophylaxis, longer courses), myringotomy, vaccinations, and xylitol.
  • Findings aim to inform clinical practice regarding AOM management and prevention in children.